L-PRF™ is a 3-D autogenous combination of Platelet Rich Fibrin derived from the patient’s blood1.
A simplified chairside procedure results in the production of a thin, compressed layer of platelet rich fibrin that is strong, pliable and suitable for suturing. This natural fibrin network is rich in platelets, growth factors and cytokines that are derived from the blood platelets and leukocytes1. The presence of these proteins have been reported to produce rapid healing, especially during the critical first seven days after placement2. This network promotes more efficient cell migration and proliferation without chemical or bovine thrombin additives3.

Clinically, Leukocyte-Platelet Rich Fibrin displays excellent working properties. This biomaterial is resilient, strong and pliable, making it easy to manipulate. It can be cut to size, and is supple enough to adapt to many anatomical areas. It is adhesive in nature and very receptive to suturing. In addition, there is ample working time since L-PRF™ is stable at room temperature for several hours4.

 Simple and economic4 
 Natural – 100% autologous4 
 Thin Fibrin Matrix & Plugs4 
 Leukocytes, Platelets and Fibrin1
 Slow Release at ≥ 7 days1
 Matrix for Bone Graft Material5

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The IntraSpin™ System establishes a three-step protocol for drawing and centrifuging the patient’s blood, removing the fi brin clot and processing it in theXpression™ Fabrication Kit. A thin, compressed layer of Platelet Rich Fibrin or plugs for extraction sites can then be formed, using either the internal plate or the piston assembly.

Applications in Dental /Oral and Maxillofacial Surgical Sites 

Including but not limited to:

• Bone defects5
• Extraction sockets1,4,5,6
• Sinus and dental ridge augmentation4,5
• Palatal defects
• Maxillary bone atrophy1,5

IntraSpin™ System is intended to be used for the safe and rapid preparation of autologus Platelet Rich Fibrin (PRF) from a small sample of blood taken at the patient’s point of care. The PRF can be mixed with autograft and/or allograft bone prior to application to a bony defect for improving handling characteristics. It requires only one centrifugation without pipetting, mixing, heating or additives. Every component of the IntraSpin™ System has been specifi cally selected and engineered to act in concert as a graft delivery. IntraSpin™ System components have been FDA cleared and are optimized to ensure proper material biocompatibility and clinical performance.

A simple three-step processing protocol necessitates drawing blood, spinning blood and expressing the fi brin clot in the Xpression™ Fabrication Kit. The system is comprised of three product groups specifi cally designed for completing this processing protocol. 

The Blood Sample Collection Set and materials have been selected for proper biocompatibilty, collection and maintenance of the blood sample.

The IntraSpin™ Centrifuge has a specific configuration and set of dynamic parameters. It has been calibrated and tested to ensure separation of the blood into proper segments and consistencies for Platelet Rich Fibrin.

The Tissue Regeneration Kit includes theXpression™ Fabrication Kit which is engineered to optimize the final step in the fabrication of Platelet Rich Fibrin. The weighted press is designed to express serum from the fibrin clot in a controlled manner and to form thin compressed layer of Platelet Rich Fibrin of a consistent thickness. A piston and cylinder assembly is used for the creation of Platelet Rich Fibrin plugs. The kit and instrumentation is also designed to aid incorporating graft material within the Platelet Rich Fibrin matrix.



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